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Tabujew, I., M. Willig, N. Leber, C. Freidel, I. Negwer, K. Koynov, M. Helm, K. Landfester, R. Zentel, K. Peneva and V. Mailänder 

Overcoming the Barrier of CD8+ T Cells: Two types of Nano-Sized Carriers for siRNA Transport., 2019 Acta Biomater., DOI: 10.1016/j.actbio.2019.10.006

https://www.sciencedirect.com/science/article/pii/S1742706119306737?via%3Dihub

Acta_biomaterialia_2019

 

Tabujew, I., C. Cokca, L. Zartner, U. S. Schubert, I. Nischang, D. Fischer and K. Peneva

The influence of gradient and statistical arrangements of guanidinium or primary amine groups in poly(methacrylate) copolymers on their DNA binding affinity. J Mater Chem B, 2019, DOI: 10.1039/C9TB01269A

https://pubs.rsc.org/en/content/articlehtml/2019/tb/c9tb01269a

 TOC_CerenCover_Ceren

  

Creusen, G., A. Roshanasan, J. Garcia Lopez, K. Peneva and A. Walther

Bottom-up design of model network elastomers and hydrogels from precise star polymers. Polym Chem 2019, (10): 3740-3750. 

https://pubs.rsc.org/en/content/articlehtml/2019/py/c9py00731h

 TOC_Walter_2019

 

Abul-Futouh, H.; Skabeev, A.; Botteri, D.; Zagranyarski, Y.; Görls, H.; Weigand, W.; Peneva, K.

Toward a Tunable Synthetic [FeFe]-Hydrogenase H-Cluster Mimic Mediated by Perylene Monoimide Model Complexes: Insight into Molecular Structures and Electrochemical Characteristics. Organometallics 2018. 37(19): 3278-3285.

 Hassan_paper_2

 

Bala, R.; Swami, A.; Tabujew, I.; Peneva, K.; Wangoo, N.; Sharma, R. K.

Ultra-sensitive detection of malathion using quantum dots-polymer based fluorescence aptasensor.  Biosens Bioelectron 2018, 104, 45-49.

http://www.sciencedirect.com/science/article/pii/S0956566317308394?via%3Dihub

Biosensors_Rohit

 

Gocheva, G.; Ilieva, N.; Peneva, K.; Ivanova, A.

Characterization of the interaction forces in a drug carrier complex of doxorubicin with a drug-binding peptide. Chemical biology & drug design 2018, 91, 874-884

http://onlinelibrary.wiley.com/doi/10.1111/cbdd.13151/full

 Drug design 2018

 

Negwer, I.; Hirsch, M.; Kaloyanova, S.; Brown, T.; Peneva, K.; Butt, H. J.; Koynov, K.; Helm, M.

Modulation of Mitochondriotropic Properties of Cyanine Dyes by in Organello Copper-Free Click Reaction. Chembiochem 2017, 18, 1814-1818.

 https://www.ncbi.nlm.nih.gov/pubmed/28704573

 In organello click

 

Lelle, M.; Freidel, C.; Kaloyanova, S.; Tabujew, I.; Schramm, A.; Musheev, M.; Niehrs, C.; Mullen, K.; Peneva, K.

Overcoming drug resistance by cell-penetrating peptide-mediated delivery of a doxorubicin dimer with high DNA-binding affinity. Eur J Med Chem 2017, 130, 336-345.

https://www.ncbi.nlm.nih.gov/pubmed/28273560

Eur j med chem

 

Lelle, M.; Freidel, C.; Kaloyanova, S.; Muellen, K.; Peneva, K.

Multivalency: Key Feature in Overcoming Drug Resistance with a Cleavable Cell-Penetrating Peptide-Doxorubicin Conjugate. 

nternational Journal of Peptide Research and Therapeutics 2018, 24, 355-367

https://link.springer.com/article/10.1007/s10989-017-9622-4

 

Hellmuth, I.; Freund, I.; Schlöder, J.; Seidu-Larry, S.; Thüring, K.; Slama, K.; Langhanki, J.; Kaloyanova, S.; Eigenbrod, T.; Krumb, M.; Röhm, S.; Peneva, K.; Opatz, T.; Jonuleit, H.; Dalpke, A.; Helm, M.

Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7). Frontiers in Immunology 2017, 8.

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00312

siRNA 2017

 

Abul-Futouh, H.; Zagranyarski, Y.; Muller, C.; Schulz, M.; Kupfer, S.; Gorls, H.; El-Khateeb, M.; Grafe, S.; Dietzek, B.; Peneva, K.; Weigand, W.

[FeFe]-Hydrogenase H-cluster mimics mediated by naphthalene monoimide derivatives of peri-substituted dichalcogenides. Dalton Trans 2017, 46, 11180-11191.

https://www.ncbi.nlm.nih.gov/pubmed/28702641

FeFe

 

Kaloyanova, S.; Zagranyarski, Y.; Ritz, S.; Hanulova, M.; Koynov, K.; Vonderheit, A.; Muellen, K.; Peneva, K.

Water-Soluble NIR-Absorbing Rylene Chromophores for Selective Staining of Cellular Organelles. J. Am. Chem. Soc. 2016, 138, 2881-2884.

http://pubs.acs.org/doi/pdfplus/10.1021/jacs.5b10425

JACS 2016

 

Freidel, C.; Kaloyanova, S.; Peneva, K.

Chemical tags for site-specific fluorescent labeling of biomolecules. Amino Acids 2016, 48, 1357-1372.

https://link.springer.com/content/pdf/10.1007%2Fs00726-016-2204-5.pdf

 

Franz, J.; Lelle, M.; Peneva, K.; Bonn, M.; Weidner, T.

SAP(E) - A cell-penetrating polyproline helix at lipid interfaces. Biochimica et Biophysica Acta, Biomembranes 2016, 1858, 2028-2034.

http://www.sciencedirect.com/science/article/pii/S000527361630195X

 

Tsoneva, Y.; Jonker, H. R. A.; Wagner, M.; Tadjer, A.; Lelle, M.; Peneva, K.; Ivanova, A.

Molecular Structure and Pronounced Conformational Flexibility of Doxorubicin in Free and Conjugated State within a Drug-Peptide Compound. Journal of Physical Chemistry B 2015, 119, 3001-3013.

http://pubs.acs.org/doi/pdfplus/10.1021/jp509320q

Dox theory paper

 

Tabujew, I.; Peneva, K.

Functionalization of Cationic Polymers for Drug Delivery Applications. In Cationic Polymers in Regenerative Medicine, Samal, S.; Dubruel, P., Eds. Royal Society of Chemistry: 2015; pp 1-29.

http://pubs.rsc.org/en/content/chapterhtml/2014/bk9781849739375-00001?isbn=978-1-84973-937-5

 

Tabujew, I.; Lelle, M.; Peneva, K.

Cell-penetrating peptides for nanomedicine – how to choose the right peptide. Bionanomaterials 2015, 16, 59-72.

https://www.degruyter.com/downloadpdf/j/biomat.2015.16.issue-1/bnm-2015-0001/bnm-2015-0001.pdf

 

Streich, C.; Koenen, S.; Lelle, M.; Peneva, K.; Barcikowski, S.

Influence of ligands in metal nanoparticle electrophoresis for the fabrication of biofunctional coatings. Applied Surface Science 2015, 348, 92-99.

http://www.sciencedirect.com/science/article/pii/S0169433214028931

 

Gold nanoparticles 

Lelle, M.; Kaloyanova, S.; Freidel, C.; Theodoropoulou, M.; Musheev, M.; Niehrs, C.; Stalla, G.; Peneva, K.

Octreotide-Mediated Tumor-Targeted Drug Delivery via a Cleavable Doxorubicin-Peptide Conjugate. Mol. Pharmaceutics 2015, 12, 4290-4300.

http://pubs.acs.org/doi/pdfplus/10.1021/acs.molpharmaceut.5b00487

Octreotide

 

Lelle, M.; Hameed, A.; Ackermann, L.-M.; Kaloyanova, S.; Wagner, M.; Berisha, F.; Nikolaev, V. O.; Peneva, K.

Functional Non-Nucleoside Adenylyl Cyclase Inhibitors. Chem. Biol. Drug Des. 2015, 85, 633-637.

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12452/full

Chem biol drug des

 

Krieg, B.; Hirsch, M.; Scholz, E.; Nuhn, L.; Tabujew, I.; Bauer, H.; Decker, S.; Khobta, A.; Schmidt, M.; Tremel, W.; Zentel, R.; Peneva, K.; Koynov, K.; Mason, A. J.; Helm, M.

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes. Pharm. Res. 2015, 32, 1957-1974.

https://link.springer.com/content/pdf/10.1007%2Fs11095-014-1589-7.pdf

HPMA Mark

 

Kantner, K.; Ashraf, S.; Carregal-Romero, S.; Carrillo-Carrion, C.; Collot, M.; del Pino, P.; Heimbrodt, W.; Jimenez De Aberasturi, D.; Kaiser, U.; Kazakova, L. I.; Lelle, M.; Martinez de Baroja, N.; Montenegro, J. M.; Nazarenus, M.; Pelaz, B.; Peneva, K.; Gil, P. R.; Sabir, N.; Schneider, L. M.; Shabarchina, L. I.; Sukhorukov, G. B.; Vazquez, M.; Yang, F.; Parak, W. J.

Particle-Based Optical Sensing of Intracellular Ions at the Example of Calcium - What Are the Experimental Pitfalls? Small 2015, 11, 896-904.

http://onlinelibrary.wiley.com/doi/10.1002/smll.201402110/abstract

 

Franz, J.; Graham, D. J.; Schmueser, L.; Baio, J. E.; Lelle, M.; Peneva, K.; Muellen, K.; Castner, D. G.; Bonn, M.; Weidner, T.

Full membrane spanning self-assembled monolayers as model systems for UHV-based studies of cell-penetrating peptides. Biointerphases 2015, 10, 1-7.

http://avs.scitation.org/doi/pdf/10.1116/1.4908164

 

Tabujew, I.; Freidel, C.; Krieg, B.; Helm, M.; Koynov, K.; Mullen, K.; Peneva, K.

The guanidinium group as a key part of water-soluble polymer carriers for siRNA complexation and protection against degradation. Macromol Rapid Commun 2014, 35, 1191-7.

http://onlinelibrary.wiley.com/wol1/doi/10.1002/marc.201400120/full

Ilja polymers

 

Lelle, M.; Peneva, K.

An amino acid-based heterofunctional cross-linking reagent. Amino Acids 2014, 46, 1243-51.

https://link.springer.com/content/pdf/10.1007%2Fs00726-014-1685-3.pdf

Amino acids 1 marco

 

Lelle, M.; Frick, S. U.; Steinbrink, K.; Peneva, K.

Novel cleavable cell-penetrating peptide-drug conjugates: synthesis and characterization. J Pept Sci 2014, 20, 323-33.

http://onlinelibrary.wiley.com/wol1/doi/10.1002/psc.2617/full

JPS

 

Wang, D.; Pevzner, L.; Li, C.; Peneva, K.; Li, C. Y.; Chan, D. Y. C.; Mullen, K.; Mezger, M.; Koynov, K.; Butt, H.-J.

Layer with reduced viscosity at water-oil interfaces probed by fluorescence correlation spectroscopy. Physical review. E, Statistical, nonlinear, and soft matter physics 2013, 87, 012403.

 

Dorresteijn, R.; Ragg, R.; Rago, G.; Billecke, N.; Bonn, M.; Parekh, S. H.; Battagliarin, G.; Peneva, K.; Wagner, M.; Klapper, M.; Muellen, K.

Biocompatible Polylactide-block-Polypeptide-block-Polylactide Nanocarrier. Biomacromolecules 2013, 14, 1572-1577.

http://pubs.acs.org/doi/abs/10.1021/bm400216r?source=chemport

 Robert abstract

 

Weil, T.; Vosch, T.; Hofkens, J.; Peneva, K.; Muellen, K.

The Rylene Colorant Family-Tailored Nanoemitters for Photonics Research and Applications. Angew Chem Int Ed 2010, 49, 9068-9093.

http://onlinelibrary.wiley.com/doi/10.1002/anie.200902532/full

 Cover

 

Peneva, K.; Gundlach, K.; Herrmann, A.; Paulsen, H.; Muellen, K.

Site-specific incorporation of perylene into an N-terminally modified light-harvesting complex II. Org Biomol Chem 2010, 8, 4823-4826.

 

Gudmand, M.; Rocha, S.; Hatzakis, N. S.; Peneva, K.; Mullen, K.; Stamou, D.; Uji-l, H.; Hofkens, J.; Bjoernholm, T.; Heimburg, T.

Influence of lipid heterogeneity and phase behavior on phospholipase A2 action at the single molecule level. Biophys J 2010, 98, 1873-1882.

 

 

Schwartz, E.; Palermo, V.; Finlayson, C. E.; Huang, Y.-S.; Otten, M. B. J.; Liscio, A.; Trapani, S.; Gonzalez-Valls, I.; Brocorens, P.; Cornelissen, J. J. L. M.; Peneva, K.; Muellen, K.; Spano, F. C.; Yartsev, A.; Westenhoff, S.; Friend, R. H.; Beljonne, D.; Nolte, R. J. M.; Samori, P.; Rowan, A. E.

"Helter-skelter-like" perylene polyisocyanopeptides. Chemistry - A European Journal 2009, 15, 2536-2547.

 Chem eur j

 

Rocha, S.; Hutchison James, A.; Peneva, K.; Herrmann, A.; Müllen, K.; Skjot, M.; Jorgensen Christian, I.; Svendsen, A.; De Schryver Frans, C.; Hofkens, J.; Uji-i, H.

Linking phospholipase mobility to activity by single-molecule wide-field microscopy. ChemPhysChem 2009, 10, 151-61.

 

 

Lebold, T.; Muehlstein, L. A.; Blechinger, J.; Riederer, M.; Amenitsch, H.; Koehn, R.; Peneva, K.; Muellen, K.; Michaelis, J.; Braeuchle, C.; Bein, T.

Tuning single-molecule dynamics in functionalized mesoporous silica. Chemistry - A European Journal 2009, 15, 1661-1672.

 

 

Jung, C.; Ruthardt, N.; Lewis, R.; Michaelis, J.; Sodeik, B.; Nolde, F.; Peneva, K.; Müllen, K.; Bräuchle, C.

Photophysics of new water-soluble terrylenediimide derivatives and applications in biology. ChemPhysChem 2009, 10, 180-90.

 

 

Gudmand, M.; Rocha, S.; Hatzakis, N. S.; Peneva, K.; Mullen, K.; Stamou, D.; Uji-I, H.; Hofkens, J.; Bjoernholm, T.; Heimburg, T.

Influence of lipid heterogeneity and phase behavior on phospholipase A2 action at the single molecule level. arXiv.org, e-Print Archive, Physics 2009, 1-10, arXiv:0907 5342v1

 

 

Cherdhirankorn, T.; Best, A.; Koynov, K.; Peneva, K.; Muellen, K.; Fytas, G.

Diffusion in polymer solutions studied by fluorescence correlation spectroscopy. Journal of Physical Chemistry B 2009, 113, 3355-3359.

 

 

Peneva, K.; Mihov, G.; Nolde, F.; Rocha, S.; Hotta, J.-i.; Braeckmans, K.; Hofkens, J.; Uji-i, H.; Herrmann, A.; Müllen, K.

Water-soluble monofunctional perylene and terrylene dyes: powerful labels for single-enzyme tracking. Angew Chem Int Ed 2008, 47, 3372-3375.

 

 

Peneva, K.; Mihov, G.; Herrmann, A.; Zarrabi, N.; Boersch, M.; Duncan, T. M.; Muellen, K.

Exploiting the Nitrilotriacetic Acid Moiety for Biolabeling with Ultrastable Perylene Dyes. J. Am. Chem. Soc. 2008, 130, 5398-5399.

 

 

Finlayson, C. E.; Friend, R. H.; Otten, M. B. J.; Schwartz, E.; Cornelissen, J. J. L. M.; Nolte, R. J. M.; Rowan, A. E.; Samori, P.; Palermo, V.; Liscio, A.; Peneva, K.; Mullen, K.; Trapani, S.; Beljonne, D.

Electronic transport properties of ensembles of perylene-substituted poly-isocyanopeptide arrays. Advanced Functional Materials 2008, 18, 3947-3955.

 

 

Tang, T.; Peneva, K.; Muellen, K.; Webber, S. E.

Photophysics of Water Soluble Perylene Diimides in Surfactant Solutions. Journal of Physical Chemistry A 2007, 111, 10609-10614.

 

 

Tang, T.; Herrmann, A.; Peneva, K.; Muellen, K.; Webber, S. E.

Energy Transfer in Molecular Layer-by-Layer Films of Water-Soluble Perylene Diimides. Langmuir 2007, 23, 4623-4628.

 

 

Momekov, G.; Deligeorgiev, T.; Vasilev, A.; Peneva, K.; Konstantinov, S.; Karaivanova, M.

Evaluation of the cytotoxic and pro-apoptotic activities of Eu(III) complexes with appended DNA intercalators in a panel of human malignant cell lines. Medicinal Chemistry 2006, 2, 439-445.

 

 

Patents:

 

Peneva, K.; Herrmann, A.; Muellen, K. Water-soluble rylene diimides dyes, methods for preparing the same and uses thereof as fluorescent labels for biomolecules. 2007-22521

2062944, 20071120., 2009.

 

Peneva, K.; Hermann, A.; Mueller, K. Water-soluble rylene diimide dyes, methods for preparing the same and uses thereof as fluorescent labels for biomolecules. WO2009065508A2, 2009.

 

 

Others:

 

Peneva, K.; Weil, T.; Muellen, K. More than just color. Detecting biomolecules with rylene fluorescence probes. GIT Labor-Fachzeitschrift 2013, 57, 34-36.