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Abul-Futouh, H.; Skabeev, A.; Botteri, D.; Zagranyarski, Y.; Görls, H.; Weigand, W.; Peneva, K.

Toward a Tunable Synthetic [FeFe]-Hydrogenase H-Cluster Mimic Mediated by Perylene Monoimide Model Complexes: Insight into Molecular Structures and Electrochemical Characteristics.

Organometallics 2018. DOI10.1021/acs.organomet.8b00450

 Hassan_paper_2

 

Bala, R.; Swami, A.; Tabujew, I.; Peneva, K.; Wangoo, N.; Sharma, R. K.

Ultra-sensitive detection of malathion using quantum dots-polymer based fluorescence aptasensor. 

Biosens Bioelectron 2018, 104, 45-49.

http://www.sciencedirect.com/science/article/pii/S0956566317308394?via%3Dihub

Biosensors_Rohit

 

Gocheva, G.; Ilieva, N.; Peneva, K.; Ivanova, A.

Characterization of the interaction forces in a drug carrier complex of doxorubicin with a drug-binding peptide. 

Chemical biology & drug design 2018, 91, 874-884

http://onlinelibrary.wiley.com/doi/10.1111/cbdd.13151/full

 Drug design 2018

 

Negwer, I.; Hirsch, M.; Kaloyanova, S.; Brown, T.; Peneva, K.; Butt, H. J.; Koynov, K.; Helm, M.

Modulation of Mitochondriotropic Properties of Cyanine Dyes by in Organello Copper-Free Click Reaction. Chembiochem 2017, 18, 1814-1818.

 https://www.ncbi.nlm.nih.gov/pubmed/28704573

 In organello click

 

Lelle, M.; Freidel, C.; Kaloyanova, S.; Tabujew, I.; Schramm, A.; Musheev, M.; Niehrs, C.; Mullen, K.; Peneva, K.

Overcoming drug resistance by cell-penetrating peptide-mediated delivery of a doxorubicin dimer with high DNA-binding affinity. Eur J Med Chem 2017, 130, 336-345.

https://www.ncbi.nlm.nih.gov/pubmed/28273560

Eur j med chem

 

Lelle, M.; Freidel, C.; Kaloyanova, S.; Muellen, K.; Peneva, K.

Multivalency: Key Feature in Overcoming Drug Resistance with a Cleavable Cell-Penetrating Peptide-Doxorubicin Conjugate. 

nternational Journal of Peptide Research and Therapeutics 2018, 24, 355-367

https://link.springer.com/article/10.1007/s10989-017-9622-4

 

Hellmuth, I.; Freund, I.; Schlöder, J.; Seidu-Larry, S.; Thüring, K.; Slama, K.; Langhanki, J.; Kaloyanova, S.; Eigenbrod, T.; Krumb, M.; Röhm, S.; Peneva, K.; Opatz, T.; Jonuleit, H.; Dalpke, A.; Helm, M.

Bioconjugation of small molecules to RNA impedes its recognition by Toll-like receptor 7 (TLR7). Frontiers in Immunology 2017, 8.

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00312

siRNA 2017

 

Abul-Futouh, H.; Zagranyarski, Y.; Muller, C.; Schulz, M.; Kupfer, S.; Gorls, H.; El-Khateeb, M.; Grafe, S.; Dietzek, B.; Peneva, K.; Weigand, W.

[FeFe]-Hydrogenase H-cluster mimics mediated by naphthalene monoimide derivatives of peri-substituted dichalcogenides. Dalton Trans 2017, 46, 11180-11191.

https://www.ncbi.nlm.nih.gov/pubmed/28702641

FeFe

 

Kaloyanova, S.; Zagranyarski, Y.; Ritz, S.; Hanulova, M.; Koynov, K.; Vonderheit, A.; Muellen, K.; Peneva, K.

Water-Soluble NIR-Absorbing Rylene Chromophores for Selective Staining of Cellular Organelles. J. Am. Chem. Soc. 2016, 138, 2881-2884.

http://pubs.acs.org/doi/pdfplus/10.1021/jacs.5b10425

JACS 2016

 

Freidel, C.; Kaloyanova, S.; Peneva, K.

Chemical tags for site-specific fluorescent labeling of biomolecules. Amino Acids 2016, 48, 1357-1372.

https://link.springer.com/content/pdf/10.1007%2Fs00726-016-2204-5.pdf

 

Franz, J.; Lelle, M.; Peneva, K.; Bonn, M.; Weidner, T.

SAP(E) - A cell-penetrating polyproline helix at lipid interfaces. Biochimica et Biophysica Acta, Biomembranes 2016, 1858, 2028-2034.

http://www.sciencedirect.com/science/article/pii/S000527361630195X

 

Tsoneva, Y.; Jonker, H. R. A.; Wagner, M.; Tadjer, A.; Lelle, M.; Peneva, K.; Ivanova, A.

Molecular Structure and Pronounced Conformational Flexibility of Doxorubicin in Free and Conjugated State within a Drug-Peptide Compound. Journal of Physical Chemistry B 2015, 119, 3001-3013.

http://pubs.acs.org/doi/pdfplus/10.1021/jp509320q

Dox theory paper

 

Tabujew, I.; Peneva, K.

Functionalization of Cationic Polymers for Drug Delivery Applications. In Cationic Polymers in Regenerative Medicine, Samal, S.; Dubruel, P., Eds. Royal Society of Chemistry: 2015; pp 1-29.

http://pubs.rsc.org/en/content/chapterhtml/2014/bk9781849739375-00001?isbn=978-1-84973-937-5

 

Tabujew, I.; Lelle, M.; Peneva, K.

Cell-penetrating peptides for nanomedicine – how to choose the right peptide. Bionanomaterials 2015, 16, 59-72.

https://www.degruyter.com/downloadpdf/j/biomat.2015.16.issue-1/bnm-2015-0001/bnm-2015-0001.pdf

 

Streich, C.; Koenen, S.; Lelle, M.; Peneva, K.; Barcikowski, S.

Influence of ligands in metal nanoparticle electrophoresis for the fabrication of biofunctional coatings. Applied Surface Science 2015, 348, 92-99.

http://www.sciencedirect.com/science/article/pii/S0169433214028931

 

Gold nanoparticles 

Lelle, M.; Kaloyanova, S.; Freidel, C.; Theodoropoulou, M.; Musheev, M.; Niehrs, C.; Stalla, G.; Peneva, K.

Octreotide-Mediated Tumor-Targeted Drug Delivery via a Cleavable Doxorubicin-Peptide Conjugate. Mol. Pharmaceutics 2015, 12, 4290-4300.

http://pubs.acs.org/doi/pdfplus/10.1021/acs.molpharmaceut.5b00487

Octreotide

 

Lelle, M.; Hameed, A.; Ackermann, L.-M.; Kaloyanova, S.; Wagner, M.; Berisha, F.; Nikolaev, V. O.; Peneva, K.

Functional Non-Nucleoside Adenylyl Cyclase Inhibitors. Chem. Biol. Drug Des. 2015, 85, 633-637.

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12452/full

Chem biol drug des

 

Krieg, B.; Hirsch, M.; Scholz, E.; Nuhn, L.; Tabujew, I.; Bauer, H.; Decker, S.; Khobta, A.; Schmidt, M.; Tremel, W.; Zentel, R.; Peneva, K.; Koynov, K.; Mason, A. J.; Helm, M.

New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes. Pharm. Res. 2015, 32, 1957-1974.

https://link.springer.com/content/pdf/10.1007%2Fs11095-014-1589-7.pdf

HPMA Mark

 

Kantner, K.; Ashraf, S.; Carregal-Romero, S.; Carrillo-Carrion, C.; Collot, M.; del Pino, P.; Heimbrodt, W.; Jimenez De Aberasturi, D.; Kaiser, U.; Kazakova, L. I.; Lelle, M.; Martinez de Baroja, N.; Montenegro, J. M.; Nazarenus, M.; Pelaz, B.; Peneva, K.; Gil, P. R.; Sabir, N.; Schneider, L. M.; Shabarchina, L. I.; Sukhorukov, G. B.; Vazquez, M.; Yang, F.; Parak, W. J.

Particle-Based Optical Sensing of Intracellular Ions at the Example of Calcium - What Are the Experimental Pitfalls? Small 2015, 11, 896-904.

http://onlinelibrary.wiley.com/doi/10.1002/smll.201402110/abstract

 

Franz, J.; Graham, D. J.; Schmueser, L.; Baio, J. E.; Lelle, M.; Peneva, K.; Muellen, K.; Castner, D. G.; Bonn, M.; Weidner, T.

Full membrane spanning self-assembled monolayers as model systems for UHV-based studies of cell-penetrating peptides. Biointerphases 2015, 10, 1-7.

http://avs.scitation.org/doi/pdf/10.1116/1.4908164

 

Tabujew, I.; Freidel, C.; Krieg, B.; Helm, M.; Koynov, K.; Mullen, K.; Peneva, K.

The guanidinium group as a key part of water-soluble polymer carriers for siRNA complexation and protection against degradation. Macromol Rapid Commun 2014, 35, 1191-7.

http://onlinelibrary.wiley.com/wol1/doi/10.1002/marc.201400120/full

Ilja polymers

 

Lelle, M.; Peneva, K.

An amino acid-based heterofunctional cross-linking reagent. Amino Acids 2014, 46, 1243-51.

https://link.springer.com/content/pdf/10.1007%2Fs00726-014-1685-3.pdf

Amino acids 1 marco

 

Lelle, M.; Frick, S. U.; Steinbrink, K.; Peneva, K.

Novel cleavable cell-penetrating peptide-drug conjugates: synthesis and characterization. J Pept Sci 2014, 20, 323-33.

http://onlinelibrary.wiley.com/wol1/doi/10.1002/psc.2617/full

JPS

 

Wang, D.; Pevzner, L.; Li, C.; Peneva, K.; Li, C. Y.; Chan, D. Y. C.; Mullen, K.; Mezger, M.; Koynov, K.; Butt, H.-J.

Layer with reduced viscosity at water-oil interfaces probed by fluorescence correlation spectroscopy. Physical review. E, Statistical, nonlinear, and soft matter physics 2013, 87, 012403.

 

Dorresteijn, R.; Ragg, R.; Rago, G.; Billecke, N.; Bonn, M.; Parekh, S. H.; Battagliarin, G.; Peneva, K.; Wagner, M.; Klapper, M.; Muellen, K.

Biocompatible Polylactide-block-Polypeptide-block-Polylactide Nanocarrier. Biomacromolecules 2013, 14, 1572-1577.

http://pubs.acs.org/doi/abs/10.1021/bm400216r?source=chemport

 Robert abstract

 

Weil, T.; Vosch, T.; Hofkens, J.; Peneva, K.; Muellen, K.

The Rylene Colorant Family-Tailored Nanoemitters for Photonics Research and Applications. Angew Chem Int Ed 2010, 49, 9068-9093.

http://onlinelibrary.wiley.com/doi/10.1002/anie.200902532/full

 Cover

 

Peneva, K.; Gundlach, K.; Herrmann, A.; Paulsen, H.; Muellen, K.

Site-specific incorporation of perylene into an N-terminally modified light-harvesting complex II. Org Biomol Chem 2010, 8, 4823-4826.

 

Gudmand, M.; Rocha, S.; Hatzakis, N. S.; Peneva, K.; Mullen, K.; Stamou, D.; Uji-l, H.; Hofkens, J.; Bjoernholm, T.; Heimburg, T.

Influence of lipid heterogeneity and phase behavior on phospholipase A2 action at the single molecule level. Biophys J 2010, 98, 1873-1882.

 

 

Schwartz, E.; Palermo, V.; Finlayson, C. E.; Huang, Y.-S.; Otten, M. B. J.; Liscio, A.; Trapani, S.; Gonzalez-Valls, I.; Brocorens, P.; Cornelissen, J. J. L. M.; Peneva, K.; Muellen, K.; Spano, F. C.; Yartsev, A.; Westenhoff, S.; Friend, R. H.; Beljonne, D.; Nolte, R. J. M.; Samori, P.; Rowan, A. E.

"Helter-skelter-like" perylene polyisocyanopeptides. Chemistry - A European Journal 2009, 15, 2536-2547.

 Chem eur j

 

Rocha, S.; Hutchison James, A.; Peneva, K.; Herrmann, A.; Müllen, K.; Skjot, M.; Jorgensen Christian, I.; Svendsen, A.; De Schryver Frans, C.; Hofkens, J.; Uji-i, H.

Linking phospholipase mobility to activity by single-molecule wide-field microscopy. ChemPhysChem 2009, 10, 151-61.

 

 

Lebold, T.; Muehlstein, L. A.; Blechinger, J.; Riederer, M.; Amenitsch, H.; Koehn, R.; Peneva, K.; Muellen, K.; Michaelis, J.; Braeuchle, C.; Bein, T.

Tuning single-molecule dynamics in functionalized mesoporous silica. Chemistry - A European Journal 2009, 15, 1661-1672.

 

 

Jung, C.; Ruthardt, N.; Lewis, R.; Michaelis, J.; Sodeik, B.; Nolde, F.; Peneva, K.; Müllen, K.; Bräuchle, C.

Photophysics of new water-soluble terrylenediimide derivatives and applications in biology. ChemPhysChem 2009, 10, 180-90.

 

 

Gudmand, M.; Rocha, S.; Hatzakis, N. S.; Peneva, K.; Mullen, K.; Stamou, D.; Uji-I, H.; Hofkens, J.; Bjoernholm, T.; Heimburg, T.

Influence of lipid heterogeneity and phase behavior on phospholipase A2 action at the single molecule level. arXiv.org, e-Print Archive, Physics 2009, 1-10, arXiv:0907 5342v1

 

 

Cherdhirankorn, T.; Best, A.; Koynov, K.; Peneva, K.; Muellen, K.; Fytas, G.

Diffusion in polymer solutions studied by fluorescence correlation spectroscopy. Journal of Physical Chemistry B 2009, 113, 3355-3359.

 

 

Peneva, K.; Mihov, G.; Nolde, F.; Rocha, S.; Hotta, J.-i.; Braeckmans, K.; Hofkens, J.; Uji-i, H.; Herrmann, A.; Müllen, K.

Water-soluble monofunctional perylene and terrylene dyes: powerful labels for single-enzyme tracking. Angew Chem Int Ed 2008, 47, 3372-3375.

 

 

Peneva, K.; Mihov, G.; Herrmann, A.; Zarrabi, N.; Boersch, M.; Duncan, T. M.; Muellen, K.

Exploiting the Nitrilotriacetic Acid Moiety for Biolabeling with Ultrastable Perylene Dyes. J. Am. Chem. Soc. 2008, 130, 5398-5399.

 

 

Finlayson, C. E.; Friend, R. H.; Otten, M. B. J.; Schwartz, E.; Cornelissen, J. J. L. M.; Nolte, R. J. M.; Rowan, A. E.; Samori, P.; Palermo, V.; Liscio, A.; Peneva, K.; Mullen, K.; Trapani, S.; Beljonne, D.

Electronic transport properties of ensembles of perylene-substituted poly-isocyanopeptide arrays. Advanced Functional Materials 2008, 18, 3947-3955.

 

 

Tang, T.; Peneva, K.; Muellen, K.; Webber, S. E.

Photophysics of Water Soluble Perylene Diimides in Surfactant Solutions. Journal of Physical Chemistry A 2007, 111, 10609-10614.

 

 

Tang, T.; Herrmann, A.; Peneva, K.; Muellen, K.; Webber, S. E.

Energy Transfer in Molecular Layer-by-Layer Films of Water-Soluble Perylene Diimides. Langmuir 2007, 23, 4623-4628.

 

 

Momekov, G.; Deligeorgiev, T.; Vasilev, A.; Peneva, K.; Konstantinov, S.; Karaivanova, M.

Evaluation of the cytotoxic and pro-apoptotic activities of Eu(III) complexes with appended DNA intercalators in a panel of human malignant cell lines. Medicinal Chemistry 2006, 2, 439-445.

 

 

Patents:

 

Peneva, K.; Herrmann, A.; Muellen, K. Water-soluble rylene diimides dyes, methods for preparing the same and uses thereof as fluorescent labels for biomolecules. 2007-22521

2062944, 20071120., 2009.

 

Peneva, K.; Hermann, A.; Mueller, K. Water-soluble rylene diimide dyes, methods for preparing the same and uses thereof as fluorescent labels for biomolecules. WO2009065508A2, 2009.

 

 

Others:

 

Peneva, K.; Weil, T.; Muellen, K. More than just color. Detecting biomolecules with rylene fluorescence probes. GIT Labor-Fachzeitschrift 2013, 57, 34-36.